Testing the effectiveness of commercial antacids and other products

Commercial antacids such as Alka SeltzerRolaids, and Tums claim to “neutralize stomach acid” by absorbing excess hydrogen ions (produced as hydrochloric acid in the stomach).

To test the abilities of these products to absorb acids, do the following:

1. Using a pipet or 10 mL graduated cylinder, add 1 ml of the antacid solution to a test tube.

2. Add 1 drop of the indicator Bromcresol purple to the tube.

3. Cover the tube with parafilm and invert the tube to mix the contents.

4. Add one drop of 0.1 M hydrochloric acid (HCl) to the tube; mix after each drop.

a. Continue this process until the solution turns yellow, indicating an acidic solution.

5. Record the number of drops of acid needed to generate the change of color.

a. This number of drops is an index to the amount of acid (H+) that the solution neutralizes before the pH drops below the yellow end-point of Bromcresol purple.

Table 3: Effectiveness of Antacids Data

Antacids Drops of Acid
Alka – Seltzer 33
Rolaids 1
Tums 1

Analysis Questions:

1. Which antacid neutralizes the acid best? Which neutralizes the acid least?

Rolaids and Tums neutralized acid best while Alka-Seltzer neutralized acid the least.

2. Examine the package of the products you tested. What are the active ingredients of each product?

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Testing the effectiveness of commercial antacids and other products was first posted on February 14, 2019 at 11:46 am.
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